In vitro anti-leishmanial activity of Sarcopoterium spinosum against Leishmania tropica
نویسندگان
چکیده
منابع مشابه
Anti-diabetic activity of aerial parts of Sarcopoterium spinosum
BACKGROUND Sarcopoterium spinosum (S. spinosum) is used by Bedouin medicinal practitioners for the treatment of diabetes. While the anti-diabetic activity of S. spinosum root extract was validated in previous studies, the activity of aerial parts of the same plants has not been elucidated yet. The aim of this study was to clarify the glucose lowering properties of the aerial parts of the shrub....
متن کاملIn vitro activity of anti-leishmanial drugs against Leishmania donovani is host cell dependent.
OBJECTIVES To evaluate the in vitro activity of anti-leishmanial drugs against intracellular Leishmania donovani amastigotes in different types of macrophages. METHODS Mouse peritoneal macrophages (PEMs), mouse bone marrow-derived macrophages (BMMPhi), human peripheral blood monocyte-derived macrophages (PBM Phi) and differentiated THP-1 cells were infected with L. donovani. Cultures were inc...
متن کاملAnti-leishmanial Activity of Methanolic Extract of Nerium oleander L. against Leishmania major
ABSTRACT Background and Objectives: Leishmaniasis is a public health problem caused by the protozoan Leishmania. Pentavalent antimonials are currently used for treatment of leishmaniasis, but they have serious side effects. Nerium oleander L. has been used in traditional medicine due to its various health-protective propertie...
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BACKGROUND Cutaneous leishmaniasis (CL) is an endemic disease in developing countries. Although pentamidine orantimonite (Glucantime) has been recommended for cutaneous leishmaniasis treatment by the World Health Organization, there are some concerns too such as high cost, side effects, need for frequent injections, and restricted efficacy. Therefore, different methods have been used for CL tre...
متن کاملIn Vitro Assessment of Miltefosine Activity Against Promastigotes and Axenic Amastigotes of Leishmania tropica
Leishmaniasis is a worldwide disease still treated with expensive compounds that present severe side effects, and are frequently ineffective emphasizing the importance to search effective compounds against this disease. Miltefosine drug (HePC) that used as antitumor agent has been used against Leishmania tropica in two forms promastigote and axenic amastigote in vitro conditions. Different conc...
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ژورنال
عنوان ژورنال: Ankara Üniversitesi Veteriner Fakültesi Dergisi
سال: 2018
ISSN: 1300-0861
DOI: 10.1501/vetfak_0000002870